| ncRNA name | rds siRNA |
| ncRNA Category | siRNA |
| Disease name | retinitis pigmentosa (RP) |
| Species | Mus musculus |
| Tissues/Cell_line | retinas |
| Methods | siRNA injection, ERG |
| Expression pattern | associated |
| Functional description | We demonstrate suppression of rds transcript by up to 50% with concomitant expression of replacement transcript in the retina of mice in vivo. The results validate the concept of suppression of rds and replacement strategies of gene therapy with rAAV vectors containing siRNA. |
| PubMed ID | 22183336 |
| Year | 2012 |
| Title | Suppression of rds expression by siRNA and gene replacement strategies for gene therapy using rAAV vector. |
| Drug-related ncRNA | NO |
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